What is PanACoTA¶
PanACoTA
(PANgenome with Annotations, COre identification, Tree and corresponding Alignments) is a software providing tools for large scale bacterial comparative genomics. You can download all refseq (or genbank) genomes for a given species, or use your set of complete and/or draft genomes, to:
Do a quality control of your strains, to eliminate poor quality genomes, which would not give any information for the comparative study
Uniformly annotate all genomes (with functional annotation, or only syntactic annotation, according to your needs)
Do a Pan-genome
Do a Core or Persistent genome
Align all Core/Persistent families
Infer a phylogenetic tree from the Core/Persistent families